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Dadun > Depósito Académico > Facultad de Ciencias > Departamento de Histología y Anatomía Patológica > DA - Ciencias - HAP - Artículos de revista >

Simple automated system for simultaneous production of 11C-labeled tracers by solid supported methylation
Authors: Quincoces, G. (Gemma)
Peñuelas, I. (Iván)
Valero, M. (Marta)
Serra, P. (Patricia)
Collantes, M. (María)
Marti-Climent, J.M. (Josep María)
Arbizu, J. (J.)
Garcia-Velloso, M.J. (María José)
Richter, J.A. (José Ángel)
Keywords: Simultaneous synthesis
[11C]methylation
[11C]methionine
[11C]choline
Issue Date: 15-Feb-2006
Publisher: Elsevier
Publisher version: http://dx.doi.org/10.1016/j.apradiso.2006.03.001
ISSN: 0969-8043
Abstract
We herein describe a simple setup for the automated simultaneous synthesis of l-[methyl-11C]methionine and N-[methyl-11C]choline by solid-supported methylation . The setup is extremely simple and easy to adapt to other automated systems and due to its versatility, the method can be utilized for the production of other radiopharmaceuticals requiring a simple [11C]methylation step. Furthermore, it can be used for multiple simultaneous synthesis.
Permanent link: http://hdl.handle.net/10171/16834
Appears in Collections:DA - CIMA - Servicios de apoyo - Micropet - Artículos de revista
DA - Ciencias - HAP - Artículos de revista

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