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http://hdl.handle.net/10171/16834
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| Title: | Simple automated system for simultaneous production of 11C-labeled tracers by solid supported methylation |
| Author(s) : | Quincoces, G. (Gemma)
Peñuelas, I. (Iván)
Valero, M. (Marta)
Serra, P. (Patricia)
Collantes, M. (M.)
Marti-Climent, J.M. (Josep M.)
Arbizu, J. (J.)
Garcia-Velloso, M. (María José)
Richter, J. (Julia) |
| Issue Date: | 2006-02-15 |
| Publisher: | Elsevier |
| Keywords: | Simultaneous synthesis
[11C]methylation
[11C]methionine
[11C]choline |
| Abstract: | We herein describe a simple setup for the automated simultaneous synthesis of l-[methyl-11C]methionine and N-[methyl-11C]choline by solid-supported methylation . The setup is extremely simple and easy to adapt to other automated systems and due to its versatility, the method can be utilized for the production of other radiopharmaceuticals requiring a simple [11C]methylation step. Furthermore, it can be used for multiple simultaneous synthesis. |
| URI: | http://hdl.handle.net/10171/16834 |
| Publisher version (URL): | http://dx.doi.org/10.1016/j.apradiso.2006.03.001 |
| Appears in Collections: | DA - CIMA - Servicios de apoyo - Micropet - Artículos de revista
DA - Ciencias - HAP - Artículos de revista
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