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Dadun >
Depósito Académico >
CIMA (Centro de Investigación Médica Aplicada) >
Área de Terapia génica y Hepatología >
Terapia génica del cáncer >

DA - CIMA - Terapia génica y Hepatología - Terapia génica del cáncer - Artículos de revista : [37]

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An oncolytic adenovirus controlled by a modified telomerase promoter is attenuated in telomerase-negative cells, but shows reduced activity in cancer cells - Bortolanza, S. (Sergia); Qian, C. (Cheng); Kramer, M.G. (María Grabiela); Gomar, C. (Celia); Prieto, J. (Jesús); Farinati, F. (F.); Hernandez-Alcoceba, R. (Rubén)

Clinical development of combination strategies in immunotherapy: are we ready for more than one investigational product in an early clinical trial? - Perez-Gracia, J.L. (José Luis); Berraondo, P. (Pedro); Martinez-Forero, I. (Iván); Alfaro, C. (Carlos); Suarez, N. (Natalia); Gurpide, A. (Alfonso); Sangro, B. (Bruno); Hervas-Stubbs, S. (Sandra); Ochoa, C. (Carmen); Melero, J.A. (José A.); Melero, I. (Ignacio)

Colon cancer eradication after chemoimmunotherapy is associated with intratumoral emergence of proinflammatory myeloid cells - Medina-Echeverz, J. (José); Berraondo, P. (Pedro)

Deletion of the E3-6.7K/gp19K region reduces the persistence of wild-type adenovirus in a permissive tumor model in Syrian hamsters - Bortolanza, S. (Sergia); Buñuales, M. (M.); Alzuguren, P. (Pilar); Lamas, O. (Oscar); Aldabe, R. (Rafael); Prieto, J. (Jesús); Hernandez-Alcoceba, R. (Rubén)

Design of virotherapy for effective tumor treatment - Garcia-Aragoncillo, E. (E.); Hernandez-Alcoceba, R. (Rubén)

Epidermal growth factor receptor ligands in murine models for erythropoietic protoporphyria: potential novel players in the progression of liver injury - Berasain, C. (Carmen); Sampedro, A. (Ana); Mauleon, I. (Itsaso); Goñi, S. (Saioa); Latasa, M.U. (María Ujué); Matscheko, N. (N); Garcia-Bravo, M. (M); Unzu, C. (Carmen); Corrales, F.J. (Fernando José); Enriquez-de-Salamanca, R. (Rafael); Prieto, J. (Jesús); Avila, M.A. (Matías Antonio); Fontanellas, A. (Antonio)

Eradication of large tumors expressing human papillomavirus E7 protein by therapeutic vaccination with E7 fused to the extra domain a from fibronectin - Mansilla, C. (Cristina); Berraondo, P. (Pedro); Durantez, M. (Maika); Martinez, M. (Marta); Casares, N. (Noelia); Arribillaga, L. (Laura); Rudilla, F. (Francesc); Fioravanti, J. (Jessica); Lozano, T. (Teresa); Villanueva, L. (Lorea); Sarobe, P. (Pablo); Borras-Cuesta, F. (Francisco); Leclerc, C. (Claude); Prieto, J. (Jesús); Lasarte, J.J. (Juan José)

Evaluation of bioluminescent imaging for noninvasive monitoring of colorectal cancer progression in the liver and its response to immunogene therapy - Zabala, M. (Maider); Alzuguren, P. (Pilar); Benavides, C. (Carolina); Crettaz, J. (Julien); Gonzalez-Aseguinolaza, G. (Gloria); Ortiz-de-Solorzano, C. (Carlos); Gonzalez-Aparicio, M. (Manuela); Kramer, M.G. (María Grabiela); Prieto, J. (Jesús); Hernandez-Alcoceba, R. (Rubén)

Evaluation of monocytes as carriers for armed oncolytic adenoviruses in murine and Syrian hamster models of cancer - Buñuales, M. (María); Garcia-Aragoncillo, E. (Eva); Casado, R. (Raquel); Quetglas, J.I. (José Ignacio); Hervas-Stubbs, S. (Sandra); Bortolanza, S. (Sergia); Benavides-Vallbe, C. (Carolina); Ortiz-de-Solorzano, C. (Carlos); Prieto, J. (Jesús); Hernandez-Alcoceba, R. (Rubén)

Gene therapy of liver cancer - Hernandez-Alcoceba, R. (Rubén); Sangro, B. (Bruno); Prieto, J. (Jesús)

Human adenovirus replicates in immunocompetent models of pancreatic cancer in syrian hamsters - Bortolanza, S. (Sergia); Alzuguren, P. (Pilar); Buñuales, M. (M.); Qian, C. (Cheng); Prieto, J. (Jesús); Hernandez-Alcoceba, R. (Rubén)

IFN-alpha gene therapy for woodchuck hepatitis with adeno-associated virus: differences in duration of gene expression and antiviral activity using intraportal or intramuscular routes - Berraondo, P. (Pedro); Ochoa, L. (Laura); Crettaz, J. (Julien); Rotellar, F. (Fernando); Vales, A. (África); Martinez-Anso, E. (Eduardo); Zaratiegui, M. (Mikel); Ruiz, J. (Juan); Gonzalez-Aseguinolaza, G. (Gloria); Prieto, J. (Jesús)

Immunochemotherapy against colon cancer by gene transfer of interleukin-12 in combination with oxaliplatin - Hernandez-Alcoceba, R. (Rubén); Berraondo, P. (Pedro)

Immunology and gene therapy: shoulder to shoulder into the fray - Smerdou, C. (Cristian); Ochoa, C. (Carmen); Quetglas, J.I. (José I.); Fontanellas, A. (Antonio); Gonzalez-Aseguinolaza, G. (Gloria); Vile, R.G. (Richard G.); Melero, I. (Ignacio)

In vivo depletion of DC impairs the anti-tumor effect of agonistic anti-CD137 mAb - Murillo, O. (Oihana); Dubrot, J. (Juan); Palazon, A. (Asís); Arina, A. (Ainhoa); Azpilicueta, A. (Arantza); Alfaro, C. (Carlos); Solano, S. (Sarai); Ochoa, M.C. (María Carmen); Berasain, C. (Carmen); Gabari, I. (Izaskun); Perez-Gracia, J.L. (José Luis); Berraondo, P. (Pedro); Hervas-Stubbs, S. (Sandra); Melero, I. (Ignacio)

Induction of gp120-specific protective immune responses by genetic vaccination with linear polyethylenimine-plasmid complex - Garzon, M. (Manolo); Berraondo, P. (Pedro); Crettaz, J. (Julien); Ochoa, L. (Laura); Vera, M. (María); Lasarte, J.J. (Juan José); Vales, A. (África); Rooijen, N. (Nico) van; Ruiz, J. (Juan); Prieto, J. (Jesús); Zulueta, J.J. (Javier J.); Gonzalez-Aseguinolaza, G. (Gloria)

Induction of immunosuppressive molecules and regulatory T cells counteracts the antitumor effect of interleukin-12-based gene therapy in a transgenic mouse model of liver cancer - Zabala, M. (Maider); Lasarte, J.J. (Juan José); Perret, C. (Christine); Sola, J. (Josu); Berraondo, P. (Pedro); Alfaro, M. (Maite); Larrea, E. (Esther); Prieto, J. (Jesús); Kramer, M.G. (María Grabiela)

Interleukin-12 inhibits liver-specific drug-inducible systems in vivo - Reboredo, M. (Mercedes); Zabala, M. (Maider); Mauleon, I. (Itsaso); Rivas, J. (Javier) de las; Kreppel, F. (Florian); Kochanek, S. (Stefan); Prieto, J. (Jesús); Hernandez-Alcoceba, R. (Rubén); Kramer, M.G. (María Grabiela)

International symposium on CTL and immunostimulation, Pamplona (Spain), October 26th and 27th 2010 - Ochoa, M.C. (María Carmen); Hervas-Stubbs, S. (Sandra); Palazon, A. (Asís); Martinez-Forero, I. (Iván); Berraondo, P. (Pedro); Sarobe, P. (Pablo); Melcher, A. (Alan); Melero, I. (Ignacio)

Intrahepatic injection of adenovirus reduces inflammation and increases gene transfer and therapeutic effect in mice - Crettaz, J. (Julien); Berraondo, P. (Pedro); Mauleon, I. (Itsaso); Ochoa, L. (Laura); Shankar, V. (Vijay); Barajas, M. (Miguel); Rooijen, N. (Nico) van; Kochanek, S. (Stefan); Qian, C. (Cheng); Prieto, J. (Jesús); Hernandez-Alcoceba, R. (Rubén); Gonzalez-Aseguinolaza, G. (Gloria)

Intrahepatic injection of recombinant adeno-associated virus serotype 2 overcomes gender-related differences in liver transduction - Berraondo, P. (Pedro); Crettaz, J. (Julien); Ochoa, L. (Laura); Pañeda, A. (Astrid); Prieto, J. (Jesús); Troconiz, I.F. (Iñaki F.); Gonzalez-Aseguinolaza, G. (Gloria)

Intratumoral injection of interferon-α and systemic delivery of agonist anti-CD137 monoclonal antibodies synergize for immunotherapy - Dubrot, J. (Juan); Palazon, A. (Asís); Alfaro, C. (Carlos); Azpilicueta, A. (Arantza); Ochoa, M.C. (María Carmen); Rouzaut, A. (Ana); Martinez-Forero, I. (Iván); Teijeira, A. (Álvaro); Berraondo, P. (Pedro); Bon, A. (Agnes) Le; Hervas-Stubbs, S. (Sandra); Melero, I. (Ignacio)

Kinetic and dynamic computational model-based characterization of new proteins in mice: application to interferon alpha linked to apolipoprotein a-I - Parra-Guillen, Z.P. (Zinnia Patricia); Fioravanti, J. (Jessica); Medina-Echeverz, J. (José); Gomer, C. (Celia); Ardaiz, N. (Nuria); Troconiz, I.F. (Iñaki F.); Berraondo, P. (Pedro)

Low surface expression of B7-1 (CD80) is an immunoescape mechanism of colon carcinoma - Tirapu, I. (Íñigo); Huarte, E. (Eduardo); Guiducci, C. (Cristiana); Arina, A. (Ainhoa); Zaratiegui, M. (Mikel); Murillo, O. (Oihana); Gonzalez, A. (Alvaro); Berasain, C. (Carmen); Berraondo, P. (Pedro); Fortes, P. (Puri); Prieto, J. (Jesús); Colombo, M.P. (Mario P.); Chen, L. (Lieping); Melero, I. (Ignacio)

Oxaliplatin in combination with liver-specific expression of interleukin 12 reduces the immunosuppressive microenvironment of tumours and eradicates metastatic colorectal cancer in mice - Gonzalez-Aparicio, M. (Manuela); Alzuguren, P. (Pilar); Mauleon, I. (Itsaso); Medina-Echeverz, J. (José); Hervas-Stubbs, S. (Sandra); Mancheño, U. (Uxua); Berraondo, P. (Pedro); Crettaz, J. (Julien); Gonzalez-Aseguinolaza, G. (Gloria); Prieto, J. (Jesús); Hernandez-Alcoceba, R. (Rubén)

Peptide inhibitors of transforming growth factor-beta enhance the efficacy of antitumor immunotherapy - Llopiz, D. (Diana); Dotor, J. (Javier); Casares, N. (Noelia); Bezunartea, J. (Jaione); Diaz-Valdes, N. (Nancy); Ruiz, M. (Marta); Aranda, F. (Fernando); Berraondo, P. (Pedro); Prieto, J. (Jesús); Lasarte, J.J. (Juan José); Borras-Cuesta, F. (Francisco); Sarobe, P. (Pablo)

Porphobilinogen deaminase over-expression in hepatocytes, but not in erythrocytes, prevents accumulation of toxic porphyrin precursors in a mouse model of acute intermittent porphyria - Unzu, C. (Carmen); Sampedro, A. (Ana); Mauleon, I. (Itsaso); Vanrell, L. (Lucía); Dubrot, J. (Juan); Enriquez-de-Salamanca, R. (Rafael); Gonzalez-Aseguinolaza, G. (Gloria); Melero, I. (Ignacio); Prieto, J. (Jesús); Fontanellas, A. (Antonio)

Production of recombinant woodchuck IFNalpha and development of monoclonal antibodies - Berraondo, P. (Pedro); Crettaz, J. (Julien); Ochoa, L. (Laura); Vales, A. (África); Ruiz, J. (Juan); Prieto, J. (Jesús); Martinez-Anso, E. (Eduardo); Gonzalez-Aseguinolaza, G. (Gloria)

Prolonged and inducible transgene expression in the liver using gutless adenovirus: a potential therapy for liver cancer - Wang, L. (Lin); Hernandez-Alcoceba, R. (Rubén); Shankar, V. (Vijay); Zabala, M. (Maider); Kochanek, S. (Stefan); Sangro, B. (Bruno); Kramer, M.G. (María Grabiela); Prieto, J. (Jesús); Qian, C. (Cheng)

Protection against woodchuck hepatitis virus (WHV) infection by gene gun coimmunization with WHV core and interleukin-12 - Garcia-Navarro, R. (Raquel); Blanco-Urgoiti, B. (Begoña); Berraondo, P. (Pedro); Sanchez-de-la-Rosa, R. (R.); Vales, A. (África); Hervas-Stubbs, S. (Sandra); Lasarte, J.J. (Juan José); Borras-Cuesta, F. (Francisco); Ruiz, J. (Juan); Prieto, J. (Jesús)

Recombinant adenoviral vectors turn on the type I interferon system without inhibition of transgene expression and viral replication - Huarte, E. (Eduardo); Larrea, E. (Esther); Hernandez-Alcoceba, R. (Rubén); Alfaro, C. (Carlos); Murillo, O. (Oihana); Arina, A. (Ainhoa); Tirapu, I. (Íñigo); Azpilicueta, A. (Arantza); Hervas-Stubbs, S. (Sandra); Bortolanza, S. (Sergia); Perez-Gracia, J.L. (José Luis); Civeira, M.P. (María Pilar); Prieto, J. (Jesús); Riezu-Boj, J.I. (José Ignacio); Melero, I. (Ignacio)

Selection of extreme phenotypes: the role of clinical observation in translational research - Perez-Gracia, J.L. (José Luis); Gurpide, A. (Alfonso); Ruiz-Ilundain, M.G. (María Gloria); Alfaro-Alegria, C. (Carlos); Colomer, R. (Ramón); Garcia-Foncillas, J. (Jesús); Melero, I. (Ignacio)

Self-inactivating helper virus for the production of high-capacity adenoviral vectors - Gonzalez-Aparicio, M. (Manuela); Mauleon, I. (Itsaso); Alzuguren, P. (Pilar); Buñuales, M. (M.); Gonzalez-Aseguinolaza, G. (Gloria); San-Martin, C. (C.); Prieto, J. (Jesús); Hernandez-Alcoceba, R. (Rubén)

Transient and intensive pharmacological immunosuppression fails to improve AAV-based liver gene transfer in non-human primates - Unzu, C. (Carmen); Hervas-Stubbs, S. (Sandra); Sampedro, A. (Ana); Mauleon, I. (Itsaso); Mancheño, U. (Uxua); Alfaro, C. (Carlos); Salamanca, E. (Enrique) de; Benito, A. (Alberto); Beatties, S.G. (Stuart G.); Pety, H. (Harald); Prieto, J. (Jesús); Melero, I. (Ignacio); Fontanellas, A. (Antonio)

Treatment of chronic viral hepatitis in woodchucks by prolonged intrahepatic expression of interleukin-12 - Crettaz, J. (Julien); Otano, I. (Itziar); Ochoa, L. (Laura); Benito, A. (Alberto); Pañeda, A. (Astrid); Aurrekoetxea, I. (Igor); Berraondo, P. (Pedro); Rodriguez-Madoz, J.R. (Juan Roberto); Astudillo, A. (Aurora); Kreppel, F. (Florian); Kochanek, S. (Stefan); Ruiz, J. (Juan); Menne, S. (Stephan); Prieto, J. (Jesús); Gonzalez-Aseguinolaza, G. (Gloria)

Treatment of pancreatic cancer with an oncolytic adenovirus expressing Interleukin-12 in syrian hamsters - Bortolanza, S. (Sergia); Buñuales, M. (M.); Otano, I. (Itziar); Gonzalez-Aseguinolaza, G. (Gloria); Ortiz-de-Solorzano, C. (Carlos); Perez, D. (Daniel); Prieto, J. (Jesús); Hernandez-Alcoceba, R. (Rubén)

Upregulation of natural killer cells functions underlies the efficacy of intratumorally injected dendritic cells engineered to produce interleukin-12 - Rodriguez-Calvillo, M. (Mercedes); Duarte, M. (Marina); Tirapu, I. (Íñigo); Berraondo, P. (Pedro); Mazzolini, G. (Guillermo); Qian, C. (Cheng); Prieto, J. (Jesús); Melero, I. (Ignacio)

DA - CIMA - Terapia génica y Hepatología - Terapia génica del cáncer - Artículos de revista : [37]

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