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Dadun > Depósito Académico > CIMA (Centro de Investigación Médica Aplicada) > Área de Oncología > Terapia celular > DA - CIMA - Oncología - Terapia celular - Artículos de Revista >

Stem Cell Therapy for Chronic Myocardial Infarction
Authors: Mazo, M. (Manuel)
Pelacho, B. (Beatriz)
Prosper, F. (Felipe)
Keywords: Chronic myocardial infarction
Stem cell
Animal models
Issue Date: 2010
Publisher: Springer Verlag
Publisher version: http://dx.doi.org/10.1007/s12265-009-9159-9
ISSN: 1937-5387
Citation: Mazo, M., Pelacho, B., Prosper, F.Stem Cell Therapy for Chronic Myocardial Infarction. J Cardiovasc Transl Res (2010) 3: 79–88
Abstract
Although recent advances for the treatment of myocardial infarction have dramatically increased the rate of survival after the ischemic event, this has also led to a rise in the number of chronic patients, making the finding of a suitable therapy a compulsory subject for modern medicine. Over the last decade, stem cells have been a promise for the cure of several diseases not only due to their plasticity but also to their capacity to act in a paracrine manner and influence the affected tissue, prompting the launching of several clinical trials. In spite of the knowledge already acquired, stem cell application to chronically infarcted hearts has been much less approached than its acute counterpart. Through this review, we will focus in stem cell therapy in animal models of chronic myocardial infarction: cell types employed, functional results, mechanisms analyzed, and questions raised.
Permanent link: http://hdl.handle.net/10171/18160
Appears in Collections:DA - CIMA - Oncología - Síndromes mieloproliferativos - Artículos de Revista
DA - CIMA - Oncología - Terapia celular - Artículos de Revista
DA - CUN - Área de Terapia Celular - Artículos de revista
DA - Medicina - Hematología - Artículos de revista

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