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Please use this identifier to cite or link to this item:
http://hdl.handle.net/10171/18566
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| Title: | Cellular Cardiomyoplasty: Clinical Application |
| Author(s) : | Chachques, J. (J.)
Acar, C. (Christophe)
Herreros, J. (Jesús)
Trainini, J. (Jorge)
Prosper, F. (Felipe)
D’Attellis, N. (N.)
Fabiani, J.N. (J.N.)
Carpentier, A. (A.) |
| Issue Date: | 2004 |
| Publisher: | Elsevier |
| Citation: | Chachques, J.C., Acar, C., Herreros, J., Trainini, J.C., Prosper, F., D’Attellis, N. et al. Cellular Cardiomyoplasty: Clinical Application. Ann. Thorac. Surg. 2004;77:1121–30 |
| Keywords: | Materias Investigacion::Ciencias de la Salud::Oncología |
| Abstract: | Myocardial regeneration can be induced with the implantation
of a variety of myogenic and angiogenic cell
types. More than 150 patients have been treated with
cellular cardiomyoplasty worldwide, 18 patients have
been treated by our group. Cellular cardiomyoplasty
seems to reduce the size and fibrosis of infarct scars, limit
postischemic remodelling, and restore regional myocardial
contractility. Techniques for skeletal myoblasts culture
and ex vivo expansion using autologous patient
serum (obtained from plasmapheresis) have been developed
by our group. In this article we propose (1) a total
autologous cell culture technique and procedures for cell
delivery and (2) a clinical trial with appropriate endpoints
structured to determine the efficacy of cellular
cardiomyoplasty. |
| URI: | http://hdl.handle.net/10171/18566 |
| Publisher version (URL): | http://dx.doi.org/10.1016/j.athoracsur.2003.09.081 |
| Appears in Collections: | DA - CIMA - Oncología - Síndromes mieloproliferativos - Artículos de Revista
DA - CIMA - Oncología - Terapia celular - Artículos de Revista
DA - CUN - Área de Terapia Celular - Artículos de revista
DA - Medicina - Hematología - Artículos de revista
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