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Dadun > Depósito Académico > CIMA (Centro de Investigación Médica Aplicada) > Área de Oncología > Genética > DA - CIMA - Oncología - Genética - Artículos de revista >

A variant t(14;17) in acute promyelocytic leukemia. Positive response to retinoic acid treatment
Authors: Cigudosa, J.C. (Juan Cruz)
Calasanz, M.J. (María José)
Odero, M.D. (María D.)
Marin, J. (Julián)
Bengoechea, E. (E.)
Gullon, A. (Arturo)
Keywords: Chromosomes, Human, Pair 14
Chromosomes, Human, Pair 17
Leukemia, Promyelocytic, Acute/genetics
Translocation, Genetic
Tretinoin/therapeutic use
Issue Date: 1995
Publisher: Elsevier
Publisher version: http://www.sciencedirect.com/science/article/pii/016546089400182B
ISSN: 1873-4456
Citation: Cigudosa JC, Calasanz MJ, Odero MD, Marin J, Bengoechea E, Gullon A. A variant t(14;17) in acute promyelocytic leukemia. Positive response to retinoic acid treatment. Cancer Genet Cytogenet 1995 Apr;80(2):160-161.
Abstract
We present a case of acute promyelocytic leukemia (APL) carrying an atypical translocation involving chromosomes 14 and 17. This translocation could be considered a variant of the APL-specific t(15;17). Positive response to retinoic acid treatment suggests molecular rearrangement of retinoic acid receptor alpha.
Permanent link: http://hdl.handle.net/10171/19795
Appears in Collections:DA - CIMA - Oncología - Genética - Artículos de revista
DA - Ciencias - Genética - Artículos de revista

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