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Please use this identifier to cite or link to this item:
http://hdl.handle.net/10171/19795
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| Title: | A variant t(14;17) in acute promyelocytic leukemia. Positive response to retinoic acid treatment |
| Author(s) : | Cigudosa, J.C. (Juan Cruz)
Calasanz, M.J. (Maria José)
Odero, M.D. (María D.)
Marin, J. (Julián)
Bengoechea, E. (E.)
Gullon, A. (Arturo) |
| Issue Date: | 1995 |
| Publisher: | Elsevier |
| Citation: | Cigudosa JC, Calasanz MJ, Odero MD, Marin J, Bengoechea E, Gullon A. A variant t(14;17) in acute promyelocytic leukemia. Positive response to retinoic acid treatment. Cancer Genet Cytogenet 1995 Apr;80(2):160-161. |
| Keywords: | Chromosomes, Human, Pair 14
Chromosomes, Human, Pair 17
Leukemia, Promyelocytic, Acute/genetics
Translocation, Genetic
Tretinoin/therapeutic use |
| Abstract: | We present a case of acute promyelocytic leukemia (APL) carrying an atypical translocation involving chromosomes 14 and 17. This translocation could be considered a variant of the APL-specific t(15;17). Positive response to retinoic acid treatment suggests molecular rearrangement of retinoic acid receptor alpha. |
| URI: | http://hdl.handle.net/10171/19795 |
| Publisher version (URL): | http://www.sciencedirect.com/science/article/pii/016546089400182B |
| Appears in Collections: | DA - CIMA - Oncología - Genética - Artículos de revista
DA - Ciencias - Genética - Artículos de revista
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