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Dadun > Depósito Académico > CIMA (Centro de Investigación Médica Aplicada) > Área de Ciencias Cardiovasculares > Cardiopatía hipertensiva > DA - CIMA - Cardiovasculares - Cardiopatía hipertensiva - Artículos de Revista >

Clinical aspects of hypertensive myocardial fibrosis
Authors: Diez, J. (Javier)
Lopez, B. (Begoña)
Gonzalez, A. (Arantxa)
Querejeta, R. (Ramón)
Keywords: Cardiomyopathies/diagnosis
Cardiomyopathies/etiology
Hypertension/complications
Myocardium/pathology
Issue Date: 2001
Publisher: Lippincott, Williams & Wilkins
Publisher version: http://journals.lww.com/co-cardiology/Abstract/2001/11000/Clinical_aspects_of_hypertensive_myocardial.3.aspx
ISSN: 0268–4705
Citation: Diez J, Lopez B, Gonzalez A, Querejeta R. Clinical aspects of hypertensive myocardial fibrosis. Curr Opin Cardiol 2001 Nov;16(6):328-335.
Abstract
Myocardial fibrosis is one of the histologic constituents of myocardial remodeling present in hypertensive patients with hypertensive heart disease. In fact, an exaggerated interstitial and perivascular accumulation of fibrillar collagens type I and type III has been found in the myocardium of patients with arterial hypertension and left ventricular hypertrophy. Hypertensive myocardial fibrosis has been shown to facilitate abnormalities of cardiac function, coronary reserve, and electrical activity that adversely affect the clinical outcome of hypertensive patients. Therefore, development of noninvasive tools for the monitoring of myocardial fibrosis and pharmacological strategies aimed to promote the regression of fibrosis could be of particular relevance in the clinical treatment of patients with hypertensive heart disease.
Permanent link: http://hdl.handle.net/10171/19844
Appears in Collections:DA - CIMA - Cardiovasculares - Cardiopatía hipertensiva - Artículos de Revista

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