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Please use this identifier to cite or link to this item:
http://hdl.handle.net/10171/21780
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| Title: | Palettes of vaccines and immunostimulatory monoclonal antibodies for combination |
| Author(s) : | Melero, I. (Ignacio)
Martinez-Forero, I. (Iván)
Dubrot, J. (Juan)
Suarez, N. (Natalia)
Palazon, A. (Asís)
Chen, L. (Lieping) |
| Issue Date: | 2009 |
| Publisher: | American Association for Cancer Research |
| Citation: | Melero I, Martinez-Forero I, Dubrot J, Suarez N, Palazon A, Chen L. Palettes of vaccines and immunostimulatory monoclonal antibodies for combination. Clin Cancer Res 2009 Mar 1;15(5):1507-1509. |
| Keywords: | Antibodies, Monoclonal/therapeutic use
Cancer Vaccines/therapeutic use
Neoplasms/therapy |
| Abstract: | Various monoclonal antibodies (mAb) target immune system molecules to enhance immunity by costimulating T cells (i.e., CD137, OX40, CD40, GITR) or interfering in coinhibitory signals (i.e., CTLA-4, PD-1). These powerful agents can be guided by cancer vaccines to enhance immunity against tumor but not self tissues. Clinically powerful therapeutic synergies are at hand. |
| URI: | http://hdl.handle.net/10171/21780 |
| Publisher version (URL): | http://clincancerres.aacrjournals.org/content/15/5/1507 |
| Appears in Collections: | DA - Medicina - Medicina Interna - Artículos de revista
DA - CIMA - Terapia génica y Hepatología - Inmunología terapia génica - Artículos de revista
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