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Dadun > Depósito Académico > CIMA (Centro de Investigación Médica Aplicada) > Área de Ciencias Cardiovasculares > Aterosclerosis e inflamación > DA - CIMA - Cardiovasculares - Aterosclerosis e inflamación - Artículos de revista >

Expansion of CD8+CD57+ T Cells in an Immunocompetent Patient with Acute Toxoplasmosis
Authors: Garcia-Muñoz, R. (R.)
Rodriguez-Otero, P. (Paula)
Galar, A. (A.)
Merino, J. (Juana)
Beunza, J.J. (Juan José)
Paramo, J.A. (José Antonio)
Lecumberri, R. (Ramón)
Keywords: Toxoplasmosis
CD8+
CD57+
Issue Date: 2009
Publisher: Hindawi Publishing Corporation
Publisher version: http://www.hindawi.com/journals/ah/2009/173439/
ISSN: 1687-9112
Citation: Garcia-Muñoz R, Rodriguez-Otero P, Galar A, Merino J, Beunza JJ, Paramo JA, et al. Expansion of CD8+CD57+ T Cells in an Immunocompetent Patient with Acute Toxoplasmosis. Adv Hematol 2009;2009:173439.
Abstract
CD57+ T cells increase in several viral infections like cytomegalovirus, herpesvirus, parvovirus, HIV and hepatitis C virus and are associated with several clinical conditions related to immune dysfunction and ageing. We report for the first time an expansion of CD8+ CD57+ T cells in a young patient with an acute infection with Toxoplasma gondii. Our report supports the concept that CD8+ CD57+ T cells could be important in the control of chronic phase of intracellular microorganisms and that the high numbers of these cells may reflect the continuing survey of the immune system, searching for parasite proliferation in the tissues.
Permanent link: http://hdl.handle.net/10171/22254
Appears in Collections:DA - CIMA - Cardiovasculares - Aterosclerosis e inflamación - Artículos de revista

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