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Estudio ecocardiográfico y de la concentración de NT-proBNP en pacientes diabéticos tipo 2 con y sin cardiopatía isquémica
Other Titles: Echocardiographic findings and NT-proBNP level in type-2 diabetic patients with and without ischemic heart disease
Authors: Castaño, S. (Sara)
Coma-Canella, I. (Isabel)
Lopez-Salazar, B. (Begoña)
Barba, J. (Joaquín)
Keywords: Diabetes mellitus, type 2/blood/complications
Myocardial ischemia/blood/complications/ultrasonography
Natriuretic peptide, brain/blood
Issue Date: 2009
Publisher: Elsevier España
Publisher version: http://dx.doi.org/10.1016/S0300-8932(09)72388-7
ISSN: 0300-8932
Citation: Castano Rodriguez S, Coma-Canella I, Lopez Salazar B, Barba Cosials J. Estudio ecocardiográfico y de la concentración de NT-proBNP en pacientes diabéticos tipo 2 con y sin cardiopatía isquémica. Rev Esp Cardiol 2009 Oct;62(10):1184-1188
Abstract
The aim of this study was to determine whether there are differences in echocardiographic findings or in the level of a biochemical marker (i.e. N-terminal probrain natriuretic peptide [NT-proBNP]) between controls and type-2 diabetic patients with or without ischemic heart disease. Echocardiography was used to assess left ventricular function and morphology. In addition, the plasma NT-proBNP concentration was measured. The prevalence of diastolic dysfunction was greater in diabetics without ischemic heart disease than in controls (88% vs. 74%, respectively; P< .001) and the NT-proBNP concentration was higher (350.6+/-197.8 vs. 281.7+/-190.4 fmol/mL; P< .001). Diabetics with ischemic heart disease had a higher NT-proBNP concentration than those without (720.4+/-278.1 vs. 350.6+/-197.8 fmol/mL, respectively; P< .001). An NT-proBNP concentration >490 fmol/mL had a sensitivity of 84% and a specificity of 75% for detecting ischemic heart disease in diabetics.
Permanent link: http://hdl.handle.net/10171/22535
Appears in Collections:DA - CUN - Cardiología - Artículos de revista

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