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Complicaciones clínicas en una serie de pacientes con anticuerpos anticardiolipina
Other Titles: Clinical complications in a series of patients with anticardiolipin antibodies
Authors: Pujol, A. (A.)
Alegria, E. (Eduardo)
Gonzalez, J. (J.)
Ngare, Ch. (Ch.)
Perez, J. (J.)
Paramo, J.A. (José Antonio)
Keywords: Antibodies, anticardiolipin/immunology
Antiphospholipid syndrome/immunology
Issue Date: 2003
Publisher: Gobierno de Navarra. Departamento de Salud
Publisher version: http://dx.doi.org/10.4321/S1137-66272003000500004
ISSN: 1137-6627
Citation: Pujol A, Alegria E, Gonzalez J, Ngare C, Perez J, Paramo JA. Complicaciones clínicas en una serie de pacientes con anticuerpos anticardiolipina. An Sist Sanit Navar 2003 Sep-Dec;26(3):365-372.
Abstract
An analysis was made of clinical complications, determined with objective methods, in 68 patients at the University Clinic of Navarra with the clinical suspicion of antiphospholipid syndrome (APS) and presence of anticardiolipin antibodies (ACA). Patients with IgG higher than 23 GPL were considered for the study. The most prevalent pathology was thrombosis: venous thrombosis (42.6%) and arterial thrombosis (22%). Other complications were abortions (23.8% of the 42 women) and thrombocytopenia (12.1%). With respect to the localisation of venous thrombosis, predominance corresponded to lower extremities (51.7%), followed by superficial thrombophlebitis (27.5%) and pulmonary thromboembolism (20.6%). Among the arterial complications, the most frequent were cerebrovascular disease (86.6 %) and coronary disease (13.4%). There was no correlation between the presence of high values of ACA and the prevalence or severity of clinical manifestations. In the series of patients with ACA IgG>23 GPL, we appreciated a high percentage of venous and arterial thrombosis detected with objective methods. The presence of ACA constitutes a prothrombotic risk factor
Permanent link: http://hdl.handle.net/10171/22673
Appears in Collections:DA - CIMA - Cardiovasculares - Aterosclerosis e inflamación - Artículos de revista
DA - CUN - Hematología y Hemoterapia - Artículos de revista

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