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Please use this identifier to cite or link to this item:
http://hdl.handle.net/10171/23060
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| Title: | Detection of anti-hepatitis C virus antibodies by ELISA using synthetic peptides |
| Author(s) : | Berasain, C. (Carmen)
Garcia-Granero, M. (Marta)
Riezu-Boj, J.I. (José Ignacio)
Civeira, M.P. (María Pilar)
Prieto, J. (Jesús)
Borras-Cuesta, F. (Francisco) |
| Issue Date: | 1993 |
| Publisher: | Elsevier |
| Citation: | Berasain C, Garcia-Granero M, Riezu-Boj JI, Civeira MP, Prieto J, Borras-Cuesta F. Detection of anti-hepatitis C virus antibodies by ELISA using synthetic peptides. J Hepatol 1993 Apr;18(1):80-84. |
| Keywords: | Hepatitis C
ELISA assay
Anti-HCV antibodies
Synthetic peptides |
| Abstract: | A novel ELISA assay for the detection of anti-hepatitis C virus antibodies in the sera of infected individuals is described. This assay is based on a mixture of three 15-amino acid synthetic peptides encompassing regions of core and NS4 proteins of hepatitis C virus. Comparison with other available ELISA assays based on recombinant polypeptides shows that, short synthetic peptides have the advantage over some larger recombinant peptides by giving higher specificity without loss of sensitivity. |
| URI: | http://hdl.handle.net/10171/23060 |
| Publisher version (URL): | http://www.sciencedirect.com/science/article/pii/S0168827805800133 |
| Appears in Collections: | DA - CIMA - Terapia génica y Hepatología - Oncobiología - Artículos de revista
DA - CUN - Medicina interna - Artículos de revista
DA - CIMA - Terapia génica y Hepatología - Virología - Artículos de revista
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