Modeling of the In Vivo Antinociceptive Interaction between an Opioid Agonist, (+)-O-Desmethyltramadol, and a Monoamine Reuptake Inhibitor, (—)-O-Desmethyltramadol, in Rats
Keywords:
Antinociception
Tramadol
Pk-pd model
Enantiomers
Publisher:
Williams & Wilkins
Citation:
Garrido MJ, Valle M, Campanero MA, Calvo R, Trocóniz IF. Modeling of the In Vivo Antinociceptive Interaction between an Opioid Agonist, (+)-O-Desmethyltramadol, and a Monoamine Reuptake Inhibitor, (—)-O-Desmethyltramadol, in Rats. J Pharmacol Exp Ther. 2000 Oct;295(1):352-9.
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