SEOM clinical guideline for the management of malignant melanoma (2017)
Keywords: 
Melanoma
Metastatic
Adjuvant
Immunotherapy
B-RAF
Issue Date: 
2018
Publisher: 
Springer
ISSN: 
1699-048X
Note: 
This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://crea tivecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
Citation: 
Berrocal, A. (A.); Arance, A. (Ana); Castellon, V.E. (V. E.); et al. "SEOM clinical guideline for the management of malignant melanoma (2017)". Clinical and translational oncology. 20 (1), 2018, 69 - 74
Abstract
All melanoma suspected patients must be confirmed histologically and resected. Sentinel node biopsy must be done when tumor is over 1 mm or if less with high-risk factors. Adjuvant therapy with interferon could be offered for patients with high-risk melanoma and in selected cases radiotherapy can be added. Metastatic melanoma treatment is guided by mutational BRAF status. BRAF wild type patients must receive anti-PD1 containing therapy and BRAF mutated patients BRAF/MEK inhibitors or anti-PD1 containing therapy. Up to 10 years follow up is reasonable for melanoma patients with dermatologic examinations and physical exams.

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