Full metadata record
DC Field | Value | Language |
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dc.creator | Moffa, A. (Antonio) | - |
dc.creator | Giorgi, L. (Lucrezia) | - |
dc.creator | Carnuccio, L. (Luca) | - |
dc.creator | Lugo, R. (Rodolfo) | - |
dc.creator | Baptista-Jardin, P. (Peter) | - |
dc.creator | Casale-Falcone, M. (Manuele) | - |
dc.date.accessioned | 2023-09-20T09:34:45Z | - |
dc.date.available | 2023-09-20T09:34:45Z | - |
dc.date.issued | 2023 | - |
dc.identifier.citation | Moffa, A.; Giorgi, L.; Carnuccio, L.; et al. "Comparison of intranasal steroid application using nasal spray and spray-sol to treat allergic rhinitis: a preliminary investigation". Journal of Clinical Medicine. 12 (10), 2023, 3492 | es |
dc.identifier.issn | 2077-0383 | - |
dc.identifier.uri | https://hdl.handle.net/10171/67254 | - |
dc.description.abstract | Allergic Rhinitis (AR) is a chronic inflammatory disease of sino-nasal mucosa, is IgE-mediated, and affects 10-40% of the global population. This study aimed to compare the efficacy of nasal administration of Beclomethasone Dipropionate (BDP) delivered via Spray-sol with nasal spray in patients suffering from AR. We included 28 AR patients assigned to one of the two following treatments: the Spray-sol group (BDP via Spray-sol) (n = 13) and the spray group (BDP using a common nasal spray) (n = 15). Both treatments were administered twice daily for 4 weeks. A nasal endoscopy evaluation and Total Nasal Symptom Score were performed at baseline and after treatment. The Spray-sol group showed better results than the spray group regarding nasal endoscopy (edema, p < 0.01; irritation, p < 0.01; secretion, p < 0.01) and nasal symptoms (nasal congestion, p < 0.05; rhinorrhea, p < 0.05; sneezing, p < 0.05; and total score, p < 0.05). No side effects were recorded. These data supported the fact that the use of BDP delivered with Spray-sol is more effective than BDP nasal spray in AR patients. Further studies are needed to confirm these encouraging results. | - |
dc.description.sponsorship | All the costs related to this study were funded by BUONA S.P.A, Via Alfieri 8-50019-Sesto Fiorentio (FI), P. IVA: 05014810484. | - |
dc.language.iso | en | - |
dc.rights | info:eu-repo/semantics/openAccess | - |
dc.subject | Impact | - |
dc.subject | Spray-sol | - |
dc.subject | Nasal device | - |
dc.subject | Nasal spray | - |
dc.subject | Beclomethasone dipropionate | - |
dc.subject | Allergic rhinitis | - |
dc.subject | Potential role | - |
dc.subject | Delivery | - |
dc.subject | Ectoine | - |
dc.title | Comparison of intranasal steroid application using nasal spray and spray-sol to treat allergic rhinitis: a preliminary investigation | - |
dc.type | info:eu-repo/semantics/article | - |
dc.description.note | This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution | - |
dc.identifier.doi | 10.3390/jcm12103492 | - |
dadun.citation.number | 10 | - |
dadun.citation.publicationName | Journal of Clinical Medicine | - |
dadun.citation.startingPage | 3492 | - |
dadun.citation.volume | 12 | - |
dc.identifier.pmid | 37240597 | - |
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